STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (389 aa)    
Predicted Functional Partners:
cbs
Cysteine synthase; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.983
KGK78789.1
Enterotoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.930
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.903
metF
MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.
  
 0.878
yitJ
Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.876
KGK80090.1
Methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.870
hom
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.853
KGK80234.1
CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
  0.847
cysE
Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.824
patB
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.817
Your Current Organism:
Thalassobacter stenotrophicus
NCBI taxonomy Id: 266809
Other names: CECT 5294, DSM 16310, Jannaschia cystaugens, Jannaschia cystaugens Adachi et al. 2004, LMG 22015 [[Jannaschia cystaugens]], LMG:22015 [[Jannaschia cystaugens]], NBRC 100362 [[Jannaschia cystaugens]], T. stenotrophicus, Thalassobacter oligotrophus, Thalassobacter sp. 1CONIMAR09, Thalassobacter stenotrophicus Macian et al. 2005, strain 5SM22, strain CFPB-A9 [[Jannaschia cystaugens]]
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