node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KGK80332.1 | KGK80334.1 | PM03_06630 | PM03_06640 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.618 |
KGK80332.1 | ureA | PM03_06630 | PM03_06620 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | 0.746 |
KGK80332.1 | ureB | PM03_06630 | PM03_06625 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.773 |
KGK80332.1 | ureC | PM03_06630 | PM03_06635 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.618 |
KGK80332.1 | ureD | PM03_06630 | PM03_06615 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.746 |
KGK80334.1 | KGK80332.1 | PM03_06640 | PM03_06630 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.618 |
KGK80334.1 | ureA | PM03_06640 | PM03_06620 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | 0.597 |
KGK80334.1 | ureB | PM03_06640 | PM03_06625 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.618 |
KGK80334.1 | ureC | PM03_06640 | PM03_06635 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
KGK80334.1 | ureD | PM03_06640 | PM03_06615 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.597 |
KGK80334.1 | ureE1 | PM03_06640 | PM03_06645 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.433 |
KGK80334.1 | ureF | PM03_06640 | PM03_06650 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.433 |
KGK80334.1 | ureG | PM03_06640 | PM03_06655 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.433 |
arcA_2 | ureA | PM03_10620 | PM03_06620 | Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | 0.869 |
arcA_2 | ureB | PM03_10620 | PM03_06625 | Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.862 |
arcA_2 | ureC | PM03_10620 | PM03_06635 | Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.861 |
kipA | ureB | PM03_12930 | PM03_06625 | Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem [...] | 0.678 |
kipA | ureC | PM03_12930 | PM03_06635 | Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.690 |
ureA | KGK80332.1 | PM03_06620 | PM03_06630 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.746 |
ureA | KGK80334.1 | PM03_06620 | PM03_06640 | Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.597 |