STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
garR_23-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)    
Predicted Functional Partners:
mmsA
Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.830
gno_2
Gluconate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.762
fadJ
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.710
ald_1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.674
glpC
Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.661
KGK79685.1
NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.660
KGK80619.1
acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.656
KGK79682.1
Amino acid transporter LysE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.640
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 
  0.639
echA8_4
enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
  0.625
Your Current Organism:
Thalassobacter stenotrophicus
NCBI taxonomy Id: 266809
Other names: CECT 5294, DSM 16310, Jannaschia cystaugens, Jannaschia cystaugens Adachi et al. 2004, LMG 22015 [[Jannaschia cystaugens]], LMG:22015 [[Jannaschia cystaugens]], NBRC 100362 [[Jannaschia cystaugens]], T. stenotrophicus, Thalassobacter oligotrophus, Thalassobacter sp. 1CONIMAR09, Thalassobacter stenotrophicus Macian et al. 2005, strain 5SM22, strain CFPB-A9 [[Jannaschia cystaugens]]
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