STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frc_1CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CoA-transferase III family. (402 aa)    
Predicted Functional Partners:
mcl2
malyl-CoA thiolesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.906
alsS
Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
 
 
 0.820
scpA_3
methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.802
scpA_1
Protein meaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.802
sucD
succinate--CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  0.743
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
  0.713
trpD_2
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
      0.692
ribF
Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family.
   
 
  0.610
fbiB
cob(II)yrinic acid a,c-diamide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.609
mcl1
malyl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.593
Your Current Organism:
Thalassobacter stenotrophicus
NCBI taxonomy Id: 266809
Other names: CECT 5294, DSM 16310, Jannaschia cystaugens, Jannaschia cystaugens Adachi et al. 2004, LMG 22015 [[Jannaschia cystaugens]], LMG:22015 [[Jannaschia cystaugens]], NBRC 100362 [[Jannaschia cystaugens]], T. stenotrophicus, Thalassobacter oligotrophus, Thalassobacter sp. 1CONIMAR09, Thalassobacter stenotrophicus Macian et al. 2005, strain 5SM22, strain CFPB-A9 [[Jannaschia cystaugens]]
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