STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFL50565.1RNA polymerase, sigma 37 subunit, RpsB/SigB; Belongs to the sigma-70 factor family. (267 aa)    
Predicted Functional Partners:
rsbW
Serine/threonine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
 
 
 0.995
SFL84501.1
Anti-sigma-28 factor, FlgM family.
  
 0.950
SFL50529.1
Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
  
 0.923
SFL50516.1
sigma-B regulation protein RsbU (phosphoserine phosphatase).
 
 
 0.922
SFL99464.1
Anti-anti-sigma regulatory factor, SpoIIAA; Belongs to the anti-sigma-factor antagonist family.
 
  
 0.874
SFL50578.1
Negative regulator of sigma-B (phosphoserine phosphatase).
 
 
 0.866
SFL74204.1
Two-component system, chemotaxis family, response regulator CheV.
  
  
 0.853
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.847
SFM30007.1
Flagellar motor switch protein FliN/FliY.
  
  
 0.845
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.830
Your Current Organism:
Salibacterium qingdaonense
NCBI taxonomy Id: 266892
Other names: Bacillus qingdaonensis, Bacillus qingdaonensis Wang et al. 2007, Bacillus sp. CM1, CGMCC 1.6134, JCM 14087, S. qingdaonense, Salibacterium qingdaonense (Wang et al. 2007) Reddy et al. 2015, strain CM1
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