STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krad_0518PFAM: protein of unknown function UPF0118; KEGG: rha:RHA1_ro00086 hypothetical protein. (397 aa)    
Predicted Functional Partners:
Krad_0519
KEGG: rxy:Rxyl_0609 putative amino acid transporter.
       0.773
Krad_0516
Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; KEGG: nfa:nfa46340 putative two-component system sensor kinase.
       0.570
Krad_0517
Two component transcriptional regulator, Fis family; PFAM: response regulator receiver; KEGG: sma:SAV2817 putative two-component system response regulator.
       0.570
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
  
     0.468
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
 
    0.462
Krad_0515
PFAM: sodium:dicarboxylate symporter; KEGG: mva:Mvan_4696 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.445
Krad_1368
PFAM: helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: tfu:Tfu_0646 ATP-dependent DNA helicase RecG.
 
     0.431
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
    0.409
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.