| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Krad_0537 | Krad_0540 | Krad_0537 | Krad_0540 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rfr:Rfer_0874 transcriptional regulator, GntR family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.451 |
| Krad_0537 | Krad_0541 | Krad_0537 | Krad_0541 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rfr:Rfer_0874 transcriptional regulator, GntR family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.451 |
| Krad_0537 | Krad_0542 | Krad_0537 | Krad_0542 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rfr:Rfer_0874 transcriptional regulator, GntR family. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sco:SCO3401 putative hydroxymethyldihydropteridine pyrophosphokinase. | 0.451 |
| Krad_0537 | Krad_0543 | Krad_0537 | Krad_0543 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rfr:Rfer_0874 transcriptional regulator, GntR family. | KEGG: sco:SCO3402 secreted protein. | 0.451 |
| Krad_0537 | folE | Krad_0537 | Krad_0539 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rfr:Rfer_0874 transcriptional regulator, GntR family. | PFAM: GTP cyclohydrolase I; KEGG: pac:PPA0261 GTP cyclohydrolase I. | 0.457 |
| Krad_0537 | ftsH | Krad_0537 | Krad_0538 | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rfr:Rfer_0874 transcriptional regulator, GntR family. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.465 |
| Krad_0540 | Krad_0537 | Krad_0540 | Krad_0537 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rfr:Rfer_0874 transcriptional regulator, GntR family. | 0.451 |
| Krad_0540 | Krad_0541 | Krad_0540 | Krad_0541 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| Krad_0540 | Krad_0542 | Krad_0540 | Krad_0542 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sco:SCO3401 putative hydroxymethyldihydropteridine pyrophosphokinase. | 0.999 |
| Krad_0540 | Krad_0543 | Krad_0540 | Krad_0543 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: sco:SCO3402 secreted protein. | 0.828 |
| Krad_0540 | folE | Krad_0540 | Krad_0539 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | PFAM: GTP cyclohydrolase I; KEGG: pac:PPA0261 GTP cyclohydrolase I. | 0.999 |
| Krad_0540 | ftsH | Krad_0540 | Krad_0538 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.874 |
| Krad_0541 | Krad_0537 | Krad_0541 | Krad_0537 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rfr:Rfer_0874 transcriptional regulator, GntR family. | 0.451 |
| Krad_0541 | Krad_0540 | Krad_0541 | Krad_0540 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| Krad_0541 | Krad_0542 | Krad_0541 | Krad_0542 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sco:SCO3401 putative hydroxymethyldihydropteridine pyrophosphokinase. | 0.999 |
| Krad_0541 | Krad_0543 | Krad_0541 | Krad_0543 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: sco:SCO3402 secreted protein. | 0.828 |
| Krad_0541 | folE | Krad_0541 | Krad_0539 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | PFAM: GTP cyclohydrolase I; KEGG: pac:PPA0261 GTP cyclohydrolase I. | 0.997 |
| Krad_0541 | ftsH | Krad_0541 | Krad_0538 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.912 |
| Krad_0542 | Krad_0537 | Krad_0542 | Krad_0537 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sco:SCO3401 putative hydroxymethyldihydropteridine pyrophosphokinase. | Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rfr:Rfer_0874 transcriptional regulator, GntR family. | 0.451 |
| Krad_0542 | Krad_0540 | Krad_0542 | Krad_0540 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: sco:SCO3401 putative hydroxymethyldihydropteridine pyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |