STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krad_0619PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: nca:Noca_0496 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase. (607 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
Krad_0620
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sma:SAV4742 putative 5-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.999
Krad_1326
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: art:Arth_3111 uroporphyrin-III C-methyltransferase.
 
 
0.994
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.992
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.960
Krad_1325
PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: fra:Francci3_0793 uroporphyrinogen III synthase HEM4.
 
 
 0.948
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: fal:FRAAL0997 glutamate-1-semialdehyde aminotransferase (aminomutase), PLP-dependent.
 
  
 0.893
Krad_0631
PFAM: cytochrome c assembly protein; KEGG: aau:AAur_pTC10173 putative cytochrome biogenesis protein.
  
    0.855
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.840
Krad_3274
PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: sma:SAV6030 putative nicotinate-nucleotide-dimethylbenzimida zole phosphoribosyltransferase.
 
  
 0.829
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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