STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (312 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.939
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.925
nadK-2
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 
0.924
Krad_1176
PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: sma:SAV3074 putative NADH pyrophosphatase.
     
 0.901
Krad_1239
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tfu:Tfu_0336 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components.
       0.613
Krad_3149
TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: tfu:Tfu_2034 hemolysin A.
  
  
 0.604
Krad_3147
TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: sco:SCO1780 putative DNA repair protein.
 
  
 0.601
Krad_3334
PFAM: ribonuclease H; Phosphoglycerate mutase; KEGG: fal:FRAAL2221 putative bifunctional protein (ribonuclease H/phosphoglycerate mutase).
  
 
  0.558
Krad_1240
PFAM: transport system permease protein; KEGG: sma:SAV6492 putative ferrichrome transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
       0.523
Krad_0138
PFAM: Alkaline phosphatase; KEGG: gvi:gll0490 phosphodiesterase/alkaline phosphatase D.
     
  0.499
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.