STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krad_1489PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: AAA ATPase; DEAD-like helicases; KEGG: nca:Noca_2329 DEAD/H associated domain protein. (1584 aa)    
Predicted Functional Partners:
Krad_1488
PFAM: Formamidopyrimidine-DNA glycolase; KEGG: sma:SAV2501 putative endonuclease VIII.
  
 0.973
Krad_0294
PFAM: Formamidopyrimidine-DNA glycolase; KEGG: fal:FRAAL5723 endonuclease VIII.
  
 0.848
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.715
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
    0.639
Krad_3854
KEGG: nca:Noca_2841 hypothetical protein.
 
  
 0.573
Krad_3247
KEGG: nca:Noca_3128 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Excinuclease ABC C subunit domain protein; Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease.
   
    0.561
Krad_3396
PFAM: Formamidopyrimidine-DNA glycolase; KEGG: nfa:nfa13280 putative formamidopyrimidine-DNA glycosylase.
  
  
 0.526
Krad_3521
DNA-(apurinic or apyrimidinic site) lyase; PFAM: Formamidopyrimidine-DNA glycolase; KEGG: tfu:Tfu_0694 putative DNA repair hydrolase; Belongs to the FPG family.
  
  
 0.526
Krad_1609
TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 3; KEGG: mkm:Mkms_5304 selenocysteine-specific translation elongation factor.
   
 
 0.497
Krad_0653
PFAM: ATP dependent DNA ligase; KEGG: rha:RHA1_ro05107 possible DNA ligase (ATP), C-terminal.
 
    0.452
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.