STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krad_1856PFAM: peptidase M50; KEGG: tfu:Tfu_1815 hypothetical protein; Belongs to the peptidase M50B family. (377 aa)    
Predicted Functional Partners:
Krad_1857
PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: aau:AAur_2173 hypothetical protein.
      0.826
Krad_1536
PFAM: PfkB domain protein; KEGG: tfu:Tfu_0696 putative 6-phosphofructokinase : 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
  
    0.672
Krad_2158
PFAM: PfkB domain protein; KEGG: aau:AAur_1468 sugar kinase.
  
    0.672
Krad_1855
KEGG: sma:SAV6672 putative RecB family exonuclease.
  
    0.659
Krad_1817
KEGG: aau:AAur_2147 hypothetical protein.
  
     0.615
Krad_1549
KEGG: sco:SCO5843 hypothetical protein.
  
     0.612
Krad_0886
KEGG: aau:AAur_0890 putative integral membrane protein.
  
     0.488
pup
Protein of unknown function DUF797; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
 
     0.418
Krad_1590
KEGG: aau:AAur_1803 hypothetical protein.
  
     0.408
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
 
     0.408
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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