STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krad_3258Cytochrome c oxidase subunit I type; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (588 aa)    
Predicted Functional Partners:
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 0.999
Krad_3250
PFAM: cytochrome c oxidase subunit III; KEGG: aau:AAur_2207 cytochrome c oxidase subunit III.
 
 0.999
Krad_3251
PFAM: cytochrome c class I; KEGG: sco:SCO2150 cytochrome C heme-binding subunit.
 
 
 0.999
Krad_3252
PFAM: Rieske [2Fe-2S] domain protein; KEGG: aau:AAur_2209 ubiquinol-cytochrome c reductase iron-sulfur subunit.
 
 
 0.999
Krad_3253
PFAM: Cytochrome b/b6 domain; KEGG: aau:AAur_2210 ubiquinol-cytochrome c reductase cytochrome b subunit.
 
 
 0.999
Krad_3257
Putative integral membrane protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
 
 
 0.999
Krad_3259
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 0.999
Krad_1467
PFAM: peptidase M16 domain protein; KEGG: aau:AAur_1571 putative Zn-dependent peptidases, family M16; Belongs to the peptidase M16 family.
   
 
 0.929
Krad_1453
PFAM: protein of unknown function DUF477; KEGG: msm:MSMEG_4484 putative conserved transmembrane protein.
   
   0.895
atpB
ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
  
 
 0.888
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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