STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (625 aa)    
Predicted Functional Partners:
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.961
Krad_2959
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: art:Arth_1693 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.944
Krad_1140
TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: mpa:MAP0829 citrate synthase; Belongs to the citrate synthase family.
   
 
 0.930
mqo
TIGRFAM: malate--quinone oxidoreductase; PFAM: FAD dependent oxidoreductase; Malate:quinone-oxidoreductase; KEGG: art:Arth_2549 malate--quinone oxidoreductase.
   
 
 0.921
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.915
Krad_2434
Pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: mka:MK0252 phosphoenolpyruvate synthase/pyruvate phosphate dikinase.
     
 0.913
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.832
Krad_3488
TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: tfu:Tfu_2856 acetate--CoA ligase.
   
 
 0.832
Krad_2227
TIGRFAM: malate synthase A; PFAM: malate synthase; KEGG: tfu:Tfu_0819 malate synthase; Belongs to the malate synthase family.
     
 0.827
Krad_4287
PFAM: Transketolase central region; Transketolase domain protein; KEGG: ace:Acel_0032 transketolase, central region.
     
 0.827
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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