STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krad_4084Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (383 aa)    
Predicted Functional Partners:
Krad_0148
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: art:Arth_0896 gamma-glutamyltransferase.
    
 0.935
Krad_3394
Protein of unknown function DUF407; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
 
  
 
0.919
Krad_3525
TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: aau:AAur_2388 aminopeptidase N.
     
 0.905
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.900
pepA-2
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.900
Krad_4482
TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: msm:MSMEG_5119 1-pyrroline-5-carboxylate dehydrogenase.
   
 
  0.805
Krad_0673
Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: sco:SCO4645 aspartate aminotransferase.
     
  0.800
Krad_1637
Glutamate--putrescine ligase; PFAM: glutamine synthetase catalytic region; KEGG: sco:SCO1613 putative glutamine synthetase.
     
  0.800
Krad_2960
TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: aau:AAur_1843 putative NADH/NADPH dependent glutamate synthases, small subunit.
     
  0.800
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.