STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krad_4168Male sterility domain; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: nca:Noca_1998 HAD-superfamily subfamily IB hydrolase, TIGR01490. (764 aa)    
Predicted Functional Partners:
Krad_4169
PFAM: phospholipid/glycerol acyltransferase; KEGG: nca:Noca_2001 phospholipid/glycerol acyltransferase.
 
 0.929
Krad_3137
PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; KEGG: fra:Francci3_2406 AMP-dependent synthetase and ligase.
  
  
 0.856
Krad_1001
PFAM: FAD linked oxidase domain protein; KEGG: fal:FRAAL2801 hypothetical protein.
 
  
 0.831
Krad_2503
PFAM: condensation domain protein; KEGG: msm:MSMEG_4963 peptide synthetase ScpsB, putative.
  
  
 0.751
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.707
hisA
TIGRFAM: bifunctional HisA/TrpF protein; PFAM: histidine biosynthesis protein; KEGG: art:Arth_1473 bifunctional HisA/TrpF protein.
  
  
 0.701
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.679
hisB
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: art:Arth_1471 imidazoleglycerol-phosphate dehydratase.
  
  
 0.656
Krad_2969
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family.
  
  
 0.636
Krad_2976
PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: tfu:Tfu_0175 phosphoribosyl-ATP pyrophosphatase; Belongs to the PRA-PH family.
  
  
 0.609
Your Current Organism:
Kineococcus radiotolerans
NCBI taxonomy Id: 266940
Other names: K. radiotolerans SRS30216 = ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149, Kineococcus radiotolerans ATCC BAA-149 = SRS30216, Kineococcus radiotolerans SRS30216, Kineococcus radiotolerans SRS30216 = ATCC BAA-149, Kineococcus-like str. SRS30216
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