node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Krad_0022 | Krad_3578 | Krad_0022 | Krad_3578 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.805 |
Krad_0022 | Krad_4231 | Krad_0022 | Krad_4231 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: art:Arth_3806 chaperone DnaJ domain protein. | 0.835 |
Krad_0022 | dnaK | Krad_0022 | Krad_4233 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.695 |
Krad_0022 | groL1 | Krad_0022 | Krad_0736 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.625 |
Krad_0022 | groL2 | Krad_0022 | Krad_3636 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.638 |
Krad_0022 | rplC | Krad_0022 | Krad_0688 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.757 |
Krad_0022 | rplM | Krad_0022 | Krad_0720 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.784 |
Krad_3578 | Krad_0022 | Krad_3578 | Krad_0022 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.805 |
Krad_3578 | Krad_4231 | Krad_3578 | Krad_4231 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: art:Arth_3806 chaperone DnaJ domain protein. | 0.821 |
Krad_3578 | groL1 | Krad_3578 | Krad_0736 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.579 |
Krad_3578 | groL2 | Krad_3578 | Krad_3636 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.579 |
Krad_3578 | grpE | Krad_3578 | Krad_4232 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.458 |
Krad_3578 | rplC | Krad_3578 | Krad_0688 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.912 |
Krad_3578 | rplM | Krad_3578 | Krad_0720 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.917 |
Krad_4230 | Krad_4231 | Krad_4230 | Krad_4231 | PFAM: regulatory protein MerR; KEGG: art:Arth_3805 transcriptional regulator, MerR family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: art:Arth_3806 chaperone DnaJ domain protein. | 0.883 |
Krad_4230 | dnaK | Krad_4230 | Krad_4233 | PFAM: regulatory protein MerR; KEGG: art:Arth_3805 transcriptional regulator, MerR family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.928 |
Krad_4230 | groL1 | Krad_4230 | Krad_0736 | PFAM: regulatory protein MerR; KEGG: art:Arth_3805 transcriptional regulator, MerR family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.432 |
Krad_4230 | groL2 | Krad_4230 | Krad_3636 | PFAM: regulatory protein MerR; KEGG: art:Arth_3805 transcriptional regulator, MerR family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.432 |
Krad_4230 | grpE | Krad_4230 | Krad_4232 | PFAM: regulatory protein MerR; KEGG: art:Arth_3805 transcriptional regulator, MerR family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.969 |
Krad_4230 | hrcA | Krad_4230 | Krad_3406 | PFAM: regulatory protein MerR; KEGG: art:Arth_3805 transcriptional regulator, MerR family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.736 |