STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched-chain-amino-acid aminotransferase; Annotated by: sma3s; COG0115. (361 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; Annotated by: sma3s; COG0129; Belongs to the IlvD/Edd family.
  
 0.971
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.957
mfs
MFS transporter; Annotated by: sma3s; COG0022; COG1071.
  
 0.948
pdhB
Pyruvate dehydrogenase E1 component subunit beta; Annotated by: sma3s; COG0022.
  
 0.926
ldh
Leucine dehydrogenase; Annotated by: sma3s; COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.919
ldh2
Leucine dehydrogenase; Annotated by: sma3s; COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.919
metB
Cystathionine gamma-synthase MetB; Annotated by: sma3s; COG0626.
   
 0.918
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.914
bkdA1
2-oxoisovalerate dehydrogenase subunit alpha; Annotated by: sma3s; COG1071.
  
 
 0.911
gshA
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
     
  0.900
Your Current Organism:
Sphingopyxis granuli
NCBI taxonomy Id: 267128
Other names: KCTC 12209, NBRC 100800, S. granuli, Sphingopyxis granuli Kim et al. 2011, Sphingopyxis sp. TFA, strain Kw07
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