STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mhpD22-keto-4-pentenoate hydratase; Annotated by: sma3s; COG3971. (259 aa)    
Predicted Functional Partners:
mhpE2
4-hydroxy-2-keto-pentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.996
mhpE
4-hydroxy-2-keto-pentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.984
mhpF2
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.971
thnD
4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoic acid hydrolase; Annotated by: sma3s; COG0596.
 
 
 0.945
amnE
4-oxalocrotonate decarboxylase; Annotated by: sma3s; COG3971.
 
  
 
0.925
mhpD
2-keto-4-pentenoate hydratase; Annotated by: sma3s; COG3971.
  
  
 
0.907
mhpF
Acetaldehyde dehydrogenase 2/3; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.880
xylF
2-hydroxy-6-oxo-2,4-heptadienoate hydrolase; Annotated by: sma3s; COG0596.
 
  
 0.757
AMG73957.1
Protocatechuate 3,4-dioxygenase; Annotated by: sma3s; COG3384.
 
  
 0.692
thnF
2,4-dihydroxydec-2-ene-1,10-dioic acid aldolase; Annotated by: sma3s; COG3836; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.683
Your Current Organism:
Sphingopyxis granuli
NCBI taxonomy Id: 267128
Other names: KCTC 12209, NBRC 100800, S. granuli, Sphingopyxis granuli Kim et al. 2011, Sphingopyxis sp. TFA, strain Kw07
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