STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMG74379.1Icl1 and ramB operon repressor protein; Annotated by: sma3s; COG3800; COG1396. (475 aa)    
Predicted Functional Partners:
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
 
   
 0.570
mutB
Methylmalonyl-CoA mutase large subunit; Annotated by: sma3s; COG1884; COG2185.
     
 0.563
aceA
Isocitrate lyase; Annotated by: sma3s; COG2224.
 
   
 0.552
pccB
Propionyl-CoA carboxylase beta chain; Annotated by: sma3s; COG4799.
     
 0.538
AMG74008.1
AraC family transcriptional regulator; Annotated by: sma3s; COG2207.
  
  
 0.477
accC4
Biotin carboxylase; Annotated by: sma3s; COG1038; COG4799.
     
 0.446
AMG75440.1
Membrane protein; Annotated by: sma3s; COG3619.
  
     0.433
nrdR
Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
   
  
 0.410
gltA
Citrate synthase; Annotated by: sma3s; COG0372; Belongs to the citrate synthase family.
  
  
 0.407
Your Current Organism:
Sphingopyxis granuli
NCBI taxonomy Id: 267128
Other names: KCTC 12209, NBRC 100800, S. granuli, Sphingopyxis granuli Kim et al. 2011, Sphingopyxis sp. TFA, strain Kw07
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