Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP0001Conserved archaeal protein. (93 aa)    
Predicted Functional Partners:
MMP0002
L-seryl-tRNA selenium transferase related protein.
  
    0.994
mcrC
Methyl coenzyme M reductase I, protein C; Citation: J. Bacteriol. 1994; 176: 6384-6391. Eur. J. Biochem. 1990; 194: 871-877.
    
   0.900
mcrA
Methyl-coenzyme M reductase I, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
  
   0.895
mcrG
Methyl-coenzyme M reductase I, gamma subunit; Citation: J. Bacterio. 1994; 176: 6384-6391. Eur. J. Biochem. 1990; 194: 871-877.
  
   0.889
mcrB
Methyl-coenzyme M reductase I, beta subunit; Citation: J. Bacteriol. 1994; 176: 6384-6391. Eur. J. Biochem. 1990; 194: 871-877.
  
   0.887
MMP0656
Conserved hypothetical protein.
   
   0.817
MMP0421
Conserved hypothetical protein.
   
   0.816
atwA
Methyl coenzyme M reductase, component A2; Citation: J. Bact. 1993 175: 3196-3203.
   
   0.816
MMP0903
Hypothetical protein.
   
    0.754
mptA
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
       0.685
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.