STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0017Conserved hypothetical protein. (350 aa)    
Predicted Functional Partners:
thi4
NAD binding site:TonB-dependent receptor protein:Thiamine biosynthesis Thi4 protein; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
     
 0.852
MMP0059
Conserved hypothetical archaeal protein.
       0.827
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.818
rpl18a
Ribosomal LX protein.
  
    0.785
MMP0865
Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.749
bioW
6-carboxyhexanoate-CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
  
  
 0.717
MMP0246
Conserved hypothetical archaeal protein.
       0.714
bioF
8-amino-7-oxononanoate synthase.
  
  
 0.705
MMP0028
Cobyric acid synthase related protein.
 
  
 0.704
MMP0247
Conserved hypothetical archaeal protein; Probably involved in the biogenesis of the ribosome.
  
    0.700
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.