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tfb protein (Methanococcus maripaludis S2) - STRING interaction network
"tfb" - Transcription initiation factor IIB in Methanococcus maripaludis S2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
tfbTranscription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) (339 aa)    
Predicted Functional Partners:
tbp
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (181 aa)
 
 
  0.999
rpm
annotation not available (105 aa)
   
 
  0.996
tfe
Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...] (185 aa)
   
 
  0.970
rpoK
annotation not available (57 aa)
   
 
  0.966
rpoD
annotation not available (180 aa)
   
 
  0.962
MMP0248
annotation not available (46 aa)
   
 
  0.955
MMP0440
annotation not available (187 aa)
   
 
  0.947
rpoL
DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (96 aa)
     
 
  0.937
rpoA2
DNA-directed RNA polymerase subunit A’’; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (386 aa)
   
 
  0.905
rpoB1
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (611 aa)
   
 
  0.893
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis S2, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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