STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0059Conserved hypothetical archaeal protein. (140 aa)    
Predicted Functional Partners:
rpl18a
Ribosomal LX protein.
  
    0.845
MMP0017
Conserved hypothetical protein.
       0.827
thi4
NAD binding site:TonB-dependent receptor protein:Thiamine biosynthesis Thi4 protein; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
       0.827
MMP0246
Conserved hypothetical archaeal protein.
       0.714
MMP0247
Conserved hypothetical archaeal protein; Probably involved in the biogenesis of the ribosome.
  
    0.700
MMP0248
DNA-directed RNA polymerase related protein.
  
    0.646
rpl37ae
Ribosomal L37ae protein; Binds to the 23S rRNA.
       0.542
aIF6
Translation initiation factor IF6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
       0.506
rpl31e
Ribosomal protein L31e; Belongs to the eukaryotic ribosomal protein eL31 family.
  
    0.466
lon
ATP-dependent Lon protease; Eukaryotic thiol (cysteine) protease, active site:ATP/GTP-binding site motif A (P-loop):Sigma-54 factor interaction domain:Pu..; Belongs to the peptidase S16 family.
       0.408
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.