STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0082Glutamate synthase; large subunit; archaeal subunit 3. (263 aa)    
Predicted Functional Partners:
MMP0080
Glutamate synthase; Citation: Nesbo CL, L'Haridon S, Stetter KO, Doolittle WF. (2001) Mol Biol Evol 18:362-75.
  
 0.998
gltB
Glutamate synthase; Citation: Nesbo CL, L'Haridon S, Stetter KO, Doolittle WF. (2001) Mol Biol Evol 18:362-75; Belongs to the glutamate synthase family.
 
    0.995
MMP0083
Conserved archaeal protein; Contains 4Fe-4S motif.
  
    0.995
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
   
    0.796
rps3ae
SSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family.
   
    0.695
idsA
Bifunctional short chain isoprenyl diphosphate synthase; Citation: Arch. Biochem. Biophys. 1994 Nov 1; 314(2):399-404; Belongs to the FPP/GGPP synthase family.
  
    0.530
MMP0496
Glutamate synthase subunit-related; Belongs to the glutamate synthase family.
 
     0.499
rpl2
LSU Ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
    0.491
rpoA2
RNA polymerase, A/beta'/A' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
    0.483
rpoA1
RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
    0.477
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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