STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0083Conserved archaeal protein; Contains 4Fe-4S motif. (359 aa)    
Predicted Functional Partners:
MMP0082
Glutamate synthase; large subunit; archaeal subunit 3.
  
    0.995
fruG
Coenzyme F420-reducing hydrogenase subunit gamma; Membrane-bound, selenium dependent; Citation: Brodersen, J. et al. 1999. Arch. Microbiol. 171:115-21. Halboth,S., Klein,A. (1992) Mol. Gen. Genet. 233:217-224.
 
 
 0.990
frcG
Coenzyme F420-reducing hydrogenase subunit gamma; Cytoplasmic, selenium independent; Citation: Muth, E. et al. 1987. Eur. J. Biochem. 169:571-7. Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Halboth,S., Klein,A.
 
 
 0.989
frcA
Coenzyme F420-reducing hydrogenase subunit alpha; Cytoplasmic, selenium independent; Citation: Muth, E. et al. 1987. Eur. J. Biochem. 169:571-7. Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Halboth,S., Klein,A; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
   
 0.985
fruA
Coenzyme F420-reducing hydrogenase subunit alpha; Contains selenocysteine; membrane-bound; Citation: Brodersen, J. et al. 1999. Arch. Microbiol. 171:115-21. Halboth,S., Klein (1992) Mol. Gen. Genet. 233:217-224; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
   
 0.985
gltB
Glutamate synthase; Citation: Nesbo CL, L'Haridon S, Stetter KO, Doolittle WF. (2001) Mol Biol Evol 18:362-75; Belongs to the glutamate synthase family.
  
  
 0.976
mer
Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
 
  
 0.950
fruD
Coenzyme F420-reducing hydrogenase delta subunit; Membrane-bound, selenium dependent; Citation: Brodersen, J. et al. 1999. Arch. Microbiol. 171:115-21. Rossmann, R., et al. 1995. Eur. J. Biochem. 2274:545-50. Halboth,S., K.
 
  
 0.928
frcD
Coenzyme F420-reducing hydrogenase subunit delta; Cytoplasmic, selenium independent; Citation: Muth, E. et al. 1987. Eur. J. Biochem. 169:571-7. Rossmann, R. et al. 1995. Eur. J. Biochem. 227:545-50. Halboth,S., Klein,A.
 
  
 0.925
MMP1337
Hydrogenase maturation protease, related; Related to frcD and fruD; Citation: Rossmann, R. et al. 1995. Eur. J. Biochem. 227:545-50.
 
  
 0.923
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.