Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP0096Aminotransferase (subgroup I); Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Andreotti G, Cubellis MV, Nitti G, Sannia G, Mai X, Adams MW, Marino G. (1995). Biochim Biophys Acta 1247:90-6. (395 aa)    
Predicted Functional Partners:
glnA
Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
  
 
 0.929
aksF
2-oxosuberate synthase, last step; Citation: J Bact 182:5013; Biochem. 37:10108.
  
 
 0.925
MMP0870
2-hydroxyacid dehydrogenase, D-isomer specific.
  
 
 0.920
ald
Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family.
    
 0.911
MMP1332
NAD binding site:FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
    
 0.908
MMP0053
Protein of unknown function DUF34.
 
    0.635
MMP0097
Transcriptional regulator protein, Helix-turn-helix motif; Helix-turn-helix motif.
     
 0.588
MMP0449
Ferredoxin.
   
   0.581
MMP0450
Ferredoxin.
   
   0.581
hdrA
Heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
   
   0.563
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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