Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP0118Conserved hypothetical protein. (205 aa)    
Predicted Functional Partners:
birA
Biotin--protein ligase; Citation: Mukhopadhyay et al., JBC273:5155 (1998).
 
  
 0.855
MMP0122
Conserved hypothetical protein.
  
  
 0.786
MMP0120
Conserved hypothetical protein; Citation: J. Biol. Chem. (2001) 276: 25654-25660.
  
    0.784
MMP0121
Hypothetical.
  
    0.768
cofC
Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
  
 0.724
MMP1570
TatD-related protein; Citation: Journal Biological Chemistry 2000 275: 16717-16722 Proteins 1997 28: 72-82.
     
 0.714
truA
tRNA pseudouridine synthase Related; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
 
 
 
 0.706
MMP0286
Conserved hypothetical protein; Belongs to the UPF0248 family.
       0.689
MMP0186
Conserved hypothetical protein; SUA5/yciO/yrdC N-terminal:Sua5/YciO/YrdC/YwlC protein family.
     
 0.668
map
Metallopeptidase family M24:Methionine aminopeptidase:Methionine aminopeptidase, subfamily 2; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
     
 0.640
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.