Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bioBBiotin synthetase. (341 aa)    
Predicted Functional Partners:
flpA
Conserved archaeal fibrillarin homolog; Citation: J Bacteriol 1994 176(7):2124-7.
  
  
 0.995
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
  
 0.925
hmd
H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenease; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
  
  
 0.903
MMP0594
Conserved hypothetical archaeal protein.
       0.827
MMP0865
Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.819
MMP1497
Conserved hypothetical protein.
     
 0.722
MMP1498
Conserved hypothetical protein.
     
 0.721
MMP0935
Conserved hypothetical protein; Belongs to the UPF0254 family.
     
 0.692
bioW
6-carboxyhexanoate-CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
  
  
 0.691
MMP1243
Conserved hypothetical archaeal protein.
     
 0.676
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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