Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
ilvEAminotransferase (subgroup III) similar to Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (287 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.995
leuA
2-isopropylmalate synthase; Citation: J. Bac. 176(15): 4590-6 [M. thermoautotrophicum] Porat. I. and Whitman, W.B. Unpublished deletion mutant; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.990
hom
Homoserine dehydrogenase; Citation: Marchenko GN, Marchenko ND, Tsygankov YD, Chistoserdov AY. (1999)Microbiology 145:3273-82.
 
 
 0.950
vorB
2-oxoisovalerate oxidoreductase subunit beta; Citation: Tersteegen, A., et al. 1997. Eur. J. Biochem. 244:862-8.
  
 
 0.918
vorA
2-oxoisovalerate oxidoreductase subunit alpha; Citation: Tersteegen, A., et al. 1997. Eur. J. Biochem. 244:862-8.
    
 0.915
vorC
2-oxoisovalerate oxidoreductase subunit gamma; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8.
    
  0.903
aksA
2-oxosuberate synthase, first step; Citation: Biochem. 37:10108; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.891
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.888
cimA
(R)-citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.876
ilvN
Acetohydroxyacid synthase small subunit.
  
 
 0.846
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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