STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAacetyl-CoA synthetase, AMP-forming; Citation: J Bact 173:6383. (636 aa)    
Predicted Functional Partners:
cdh
CO dehydrogenase/acetyl-CoA synthase complex subunit gamma; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
  
 
 0.976
acd
acetyl-CoA synthetase (ADP-forming), alpha and beta subunits; Citation: J Bact 181:5885.
  
 
 0.975
cdhB
CO dehydrogenase/acetyl-CoA synthase complex subunit beta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
  
 
 0.968
MMP1212
Unnamed protein product.
  
 
 0.968
cdhD
CO dehydrogenase/acetyl-CoA synthase subunit delta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
  
 
 0.964
MMP0348
Conserved hypothetical protein; GPR1/FUN34/yaaH family.
  
  
 0.956
leuA
2-isopropylmalate synthase; Citation: J. Bac. 176(15): 4590-6 [M. thermoautotrophicum] Porat. I. and Whitman, W.B. Unpublished deletion mutant; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.937
porC
Pyruvate oxidoreductase (synthase) subunit gamma; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8; Lin, WC et al, Arch Microbiol 179:444 (2003).
  
 
 0.937
aksA
2-oxosuberate synthase, first step; Citation: Biochem. 37:10108; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.932
porD
Pyruvate oxidoreductase (synthase) subunit delta; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8; Lin, WC et al, Arch Microbiol 179:444 (2003).
  
 
 0.932
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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