STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comB2-phosphosulfolactate phosphatase; Citation: Eur. J. Biochem. 268:5176-5188(2001). (248 aa)    
Predicted Functional Partners:
comA
(2R)-phospho-3-sulfolactate synthase; Citation: J. Biol. Chem. 277:13421-13429(2002).
 
 0.999
comC
L-sulfolactate dehydrogenase/(S)-hydroxyglutaric acid dehydrogenase; Citation: J. Bacteriol. 182:3688-3692(2000).
  
 
 0.995
MMP1356
Conserved hypothetical protein.
   
 
 0.880
MMP1393
Conserved hypothetical protein.
   
    0.858
rnp3
Conserved hypothetical Archael protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
 
    0.856
comE
Sulfopyruvate decarboxylase subunit beta; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde.
      
 0.802
upp
Uracil Phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate; Belongs to the UPRTase family.
 
  
 0.720
mtaA
Uroporphyrinogen decarboxylase (URO-D).
  
  
 0.685
mtaA-2
Uroporphyrinogen decarboxylase (URO-D).
  
  
 0.685
MMP1357
ThiamineS.
  
  
 0.674
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.