Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arsAPutative arsenical pump-driving ATPase. (345 aa)    
Predicted Functional Partners:
MMP0162
Conserved hypothetical protein.
  
  
 0.929
MMP0176
CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893.
 
 
 0.858
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
    
 
 0.830
pycB
Pyruvate carboxylase subunit B; Citation: JBC 273:5155.
  
    0.776
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
    
 
 0.738
psmB
Proteasome, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
  
 
 0.718
MMP0190
Conserved hypothetical protein; Similar to fragment of K+-dependent Na+/Ca+ exchanger protein.
  
   0.682
MMP1068
K+-dependent Na+/Ca+ exchanger related-protein:Sodium/calcium exchanger membrane region.
  
   0.682
MMP0276
Conserved hypothetical protein.
    
 0.662
MMP0673
TPR repeat.
    
 0.662
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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