Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP0169Conserved hypothetical protein. (375 aa)    
Predicted Functional Partners:
cofF
gamma-F420-2:alpha-L-glutamate ligase; Catalyzes the ATP-dependent addition of one alpha-linked L- glutamate molecule to coenzyme gamma-F420-2, producing coenzyme alpha- F420-3. Thus, caps the gamma-polyglutamate tail of coenzyme F420 with a terminal alpha-linked glutamate (By similarity).
  
  
 0.825
uppS
Undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
  
  
 0.765
MMP0171
Conserved hypothetical protein.
  
    0.738
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.715
MMP1356
Conserved hypothetical protein.
  
  
 0.711
MMP0167
ABC transporter ATP binding protein family member.
  
  
 0.667
MMP0168
Transcriptional regulator PadR-like family.
 
  
 0.662
MMP1163
CutA1 divalent ion tolerance protein Related Protein.
       0.616
MMP1192
Conserved hypothetical protein.
       0.616
hisS
histidyl-tRNA synthetase; Citation: J Biol Chem 1985 Aug 25;260(18):10063-8; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.606
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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