| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MMP0176 | hsp60 | MMP0176 | MMP1515 | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family. | 0.876 |
| MMP0176 | map | MMP0176 | MMP1444 | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | Metallopeptidase family M24:Methionine aminopeptidase:Methionine aminopeptidase, subfamily 2; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. | 0.917 |
| MMP0176 | psmA | MMP0176 | MMP0251 | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | Proteasome, subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.965 |
| MMP0176 | psmB | MMP0176 | MMP0695 | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | Proteasome, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.938 |
| MMP0176 | psmR | MMP0176 | MMP1647 | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | Proteasome-activating nucleotidase (PAN); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes A [...] | 0.895 |
| MMP0176 | radA | MMP0176 | MMP1222 | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.868 |
| MMP0176 | radB | MMP0176 | MMP0617 | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | DNA repair and recombination protein radB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity). | 0.885 |
| MMP0176 | rpl10 | MMP0176 | MMP0259 | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.873 |
| MMP0176 | rpl2 | MMP0176 | MMP1546 | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | LSU Ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.881 |
| MMP0176 | rpl40e | MMP0176 | MMP0151 | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.964 |
| hsp60 | MMP0176 | MMP1515 | MMP0176 | Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family. | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | 0.876 |
| hsp60 | map | MMP1515 | MMP1444 | Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family. | Metallopeptidase family M24:Methionine aminopeptidase:Methionine aminopeptidase, subfamily 2; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. | 0.702 |
| hsp60 | psmA | MMP1515 | MMP0251 | Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family. | Proteasome, subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.777 |
| hsp60 | psmB | MMP1515 | MMP0695 | Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family. | Proteasome, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.652 |
| hsp60 | psmR | MMP1515 | MMP1647 | Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family. | Proteasome-activating nucleotidase (PAN); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes A [...] | 0.582 |
| hsp60 | radA | MMP1515 | MMP1222 | Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family. | DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.700 |
| hsp60 | radB | MMP1515 | MMP0617 | Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family. | DNA repair and recombination protein radB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity). | 0.472 |
| hsp60 | rpl10 | MMP1515 | MMP0259 | Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family. | LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.740 |
| hsp60 | rpl2 | MMP1515 | MMP1546 | Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family. | LSU Ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.723 |
| map | MMP0176 | MMP1444 | MMP0176 | Metallopeptidase family M24:Methionine aminopeptidase:Methionine aminopeptidase, subfamily 2; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. | CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893. | 0.917 |