STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0220Sodium/proline symporter-related; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (489 aa)    
Predicted Functional Partners:
gapN
Aldehyde dehydrogenase; Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate.
  
  
 0.684
MMP0229
ABC amino acid transport ATP binding protein.
  
  
 0.660
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
 0.614
hpt
Hypoxanthine (guanine) phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
  
  
 0.597
MMP1274
acetyl-CoA synthetase, AMP-forming-related; Citation: J Bact 173:6383.
 
  
 0.578
hemL
Glutamate-1-semialdehyde aminotransferase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
  
  
 0.566
putP
Sodium/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
   
0.564
acsA
acetyl-CoA synthetase, AMP-forming; Citation: J Bact 173:6383.
  
  
 0.516
ppaC
Inorganic pyrophosphatase, manganese-dependent; Citation: Kuhn,N.J., Wadeson,A., Ward,S., Young,T.W., (2000) Arch. Biochem. Biophys. 379:292-298.
       0.478
agcS
Sodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake.
  
  
 0.454
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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