STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmAProteasome, subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. (259 aa)    
Predicted Functional Partners:
psmB
Proteasome, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
 
0.999
psmR
Proteasome-activating nucleotidase (PAN); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes A [...]
 0.998
MMP0176
CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893.
 0.965
rpl40e
LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.944
MMP0914
Conserved hypothetical archaeal protein.
   
 
 0.921
MMP1530
Conserved hypothetical protein.
   
  
 0.869
rpl15
LSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family.
  
 0.860
MMP0250
Conserved hypothetical protein.
 
  
 0.855
rpl37ae
Ribosomal L37ae protein; Binds to the 23S rRNA.
 
  
 0.854
MMP1611
Conserved hypothetical protein.
  
 
 0.830
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.