Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP0262Conserved hypothetical protein. (205 aa)    
Predicted Functional Partners:
rpoL
DNA directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
  
  
 0.986
rpoD
DNA-directed RNA polymerase, subunit D.
   
  
 0.661
MMP0188
Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
       0.616
thrS
Threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.616
MMP0685
SAM (and some other nucleotide) binding motif:N-6 Adenine-specific DNA methylase.
       0.616
rpl10e
Ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family.
       0.615
MMP0155
Conserved hypothetical protein.
   
  
 0.571
MMP1099
Phosphate ABC transporter, regulatory protein; Plays a role in the regulation of phosphate uptake.
   
  
 0.544
MMP1661
Hypothetical protein.
      
 0.533
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
  
    0.522
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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