close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0266Integral membrane protein of the MarC family. (213 aa)    
Predicted Functional Partners:
MMP0267
Conserved hypothetical archaeal protein.
  
    0.944
truA
tRNA pseudouridine synthase Related; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
  
  
 0.768
MMP0269
Conserved hypothetical protein.
  
    0.461
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate.
  
    0.448
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
    0.432
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
  
    0.431
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
       0.408
purD
Phosphoribosylamine--glycine ligase; Citation: Kanai S, Toh H. (1999) J Mol Evol 48:482-92.
       0.408
pyrK
2Fe-2S Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:NADH:cytochrome b5 reductase (CBR); Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
       0.408
MMP1055
Conserved hypothetical protein; Belongs to the UPF0235 family.
       0.408
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.