STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comA(2R)-phospho-3-sulfolactate synthase; Citation: J. Biol. Chem. 277:13421-13429(2002). (235 aa)    
Predicted Functional Partners:
comB
2-phosphosulfolactate phosphatase; Citation: Eur. J. Biochem. 268:5176-5188(2001).
 
 0.999
MMP0272
ABC transporter ATPase subunit.
  
    0.990
MMP0271
ATP binding putative nickel incorporation protein.
  
    0.988
MMP0270
Conserved archaeal protein.
  
    0.986
comD
Sulfopyruvate decarboxylase subunit alpha; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde; Belongs to the ComD family.
  
  
 0.942
comC
L-sulfolactate dehydrogenase/(S)-hydroxyglutaric acid dehydrogenase; Citation: J. Bacteriol. 182:3688-3692(2000).
     
 0.868
MMP0141
Conserved archaeal protein; Probable Zn finger protein; Prokaryotic DNA topoisomerase I-related (C-term).
  
    0.853
2pgk
2-phosphoglycerate kinase; Citation: Mol. Gen. Genet. 242 (2), 163-168 (1994); FEBS Lett. 272:94-98.
   
  
 0.818
comE
Sulfopyruvate decarboxylase subunit beta; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde.
  
  
 0.684
mtrD
N5-methyltetrahydromethanopterin: methyltransferase, subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
      
 0.646
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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