Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MMP0287Conserved Hypothetical protein with 2 CBS domains. (264 aa)    
Predicted Functional Partners:
MMP0285
Phosphoesterase, RecJ-like:TrkA-N:Phosphoesterase, DHHA1.
 
    0.867
MMP0286
Conserved hypothetical protein; Belongs to the UPF0248 family.
  
    0.842
MMP0967
Serine/threonine dehydratase, pyridoxal-phosphate attachment site.
       0.827
MMP0288
Conserved hypothetical archeal protein.
  
    0.739
pcnA
Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
  
  
 0.592
smc1
Structural maintenance of chromosome protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.586
infB
Translation inititation factor aIF2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
     
 0.574
MMP0029
Conserved hypothetical archeal protein.
  
    0.524
MMP1517
Conserved hypothetical protein.
 
  
 0.515
MMP0052
Conserved Hypothetical protein with 2 CBS domains.
  
     0.514
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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