Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP0303Rubredoxin; Citation: J. Biol. Inorg. Chem. 3, 484 (1998). (45 aa)    
Predicted Functional Partners:
rbo
Desulfoferrodoxin, ferrous iron-binding site.
     
 0.873
MMP1677
4-hydroxybenzoate octaprenyl transferase related protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
     
 0.708
MMP1174
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
     
 0.673
porF
Conserved archaeal protein, pyruvate oxidoreductase-associated; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
     
 0.666
MMP1159
Ferritin.
     
 0.636
MMP0304
Conserved hypothetical archaeal protein; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates.
  
    0.630
MMP0306
Oxidoreductase family member subunit alpha; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8.
  
  
 0.599
MMP0633
Rubrerythrin.
  
  
 0.584
MMP1136
Rubrerythrin.
  
  
 0.584
MMP0305
Oxidoreductase family member subunit beta; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8.
  
  
 0.580
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (14%) [HD]