| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MMP0188 | MMP0307 | MMP0188 | MMP0307 | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Conserved hypothetical archaeal protein. | 0.408 |
| MMP0188 | MMP1605 | MMP0188 | MMP1605 | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.402 |
| MMP0188 | tyrA | MMP0188 | MMP1514 | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Prephenate dehydrogenase; Citation: MacBeath G, Kast P, Hilvert D. (1998) Biochemistry 37:10062-73. | 0.646 |
| MMP0304 | MMP0305 | MMP0304 | MMP0305 | Conserved hypothetical archaeal protein; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates. | Oxidoreductase family member subunit beta; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | 0.712 |
| MMP0304 | MMP0306 | MMP0304 | MMP0306 | Conserved hypothetical archaeal protein; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates. | Oxidoreductase family member subunit alpha; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | 0.675 |
| MMP0304 | MMP0307 | MMP0304 | MMP0307 | Conserved hypothetical archaeal protein; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates. | Conserved hypothetical archaeal protein. | 0.558 |
| MMP0305 | MMP0304 | MMP0305 | MMP0304 | Oxidoreductase family member subunit beta; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | Conserved hypothetical archaeal protein; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates. | 0.712 |
| MMP0305 | MMP0306 | MMP0305 | MMP0306 | Oxidoreductase family member subunit beta; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | Oxidoreductase family member subunit alpha; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | 0.999 |
| MMP0305 | MMP0307 | MMP0305 | MMP0307 | Oxidoreductase family member subunit beta; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | Conserved hypothetical archaeal protein. | 0.586 |
| MMP0305 | MMP0308 | MMP0305 | MMP0308 | Oxidoreductase family member subunit beta; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | Conserved hypothetical archaeal protein. | 0.475 |
| MMP0305 | MMP1605 | MMP0305 | MMP1605 | Oxidoreductase family member subunit beta; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.936 |
| MMP0306 | MMP0304 | MMP0306 | MMP0304 | Oxidoreductase family member subunit alpha; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | Conserved hypothetical archaeal protein; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates. | 0.675 |
| MMP0306 | MMP0305 | MMP0306 | MMP0305 | Oxidoreductase family member subunit alpha; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | Oxidoreductase family member subunit beta; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | 0.999 |
| MMP0306 | MMP0307 | MMP0306 | MMP0307 | Oxidoreductase family member subunit alpha; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | Conserved hypothetical archaeal protein. | 0.597 |
| MMP0306 | MMP1605 | MMP0306 | MMP1605 | Oxidoreductase family member subunit alpha; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.929 |
| MMP0307 | MMP0188 | MMP0307 | MMP0188 | Conserved hypothetical archaeal protein. | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.408 |
| MMP0307 | MMP0304 | MMP0307 | MMP0304 | Conserved hypothetical archaeal protein. | Conserved hypothetical archaeal protein; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates. | 0.558 |
| MMP0307 | MMP0305 | MMP0307 | MMP0305 | Conserved hypothetical archaeal protein. | Oxidoreductase family member subunit beta; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | 0.586 |
| MMP0307 | MMP0306 | MMP0307 | MMP0306 | Conserved hypothetical archaeal protein. | Oxidoreductase family member subunit alpha; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8. | 0.597 |
| MMP0307 | MMP0308 | MMP0307 | MMP0308 | Conserved hypothetical archaeal protein. | Conserved hypothetical archaeal protein. | 0.488 |