Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP0324Conserved hypothetical archaeal protein. (126 aa)    
Predicted Functional Partners:
MMP0374
Conserved hypothetical protein.
       0.802
metS
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
       0.763
mptA
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
       0.689
aIF-1A
Translation initiation factor 1A (aIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
       0.689
MMP0604
Conserved Hypothetical Protein.
       0.689
MMP0605
Conserved Hypothetical protein.
       0.689
MMP0950
Conserved hypothetical protein.
       0.689
top6B
DNA topoisomerase VI B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
       0.689
top6A
DNA topoisomerase VI A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
       0.689
MMP0323
Hypothetical methyltransferase protein.
  
    0.678
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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