Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP0335Conserved hypothetical protein. (137 aa)    
Predicted Functional Partners:
MMP0378
Atrazine chlorohydrolase related protein; Citation: J. Bacteriol. 178: 4894-4900 (1996).
      
 0.773
thyA
Thymidylate synthase; Citation: Xu et al., Nature Structural. Biol. 6, 750 (1999).
      
 0.773
MMP1718
Conserved hypothetical archeal protein.
   
  
 0.664
selB
Archaeal translation factor specialized for selenocysteine insertion; Citation: J Bacteriol. 2003 Jan;185(1):107-14.
       0.645
wbpI
UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP- ManNAc), the activated donor of ManNAc residues.
      
 0.633
pheT
Phenylalanyl-tRNA synthetase beta subunit.
      
 0.630
MMP1611
Conserved hypothetical protein.
      
 0.610
MMP0334
rRNA methyltransferase related protein.
       0.582
dacZ
Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
   
  
 0.576
hdrC1
Heterosulfide reductase, subunit C1; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrC family.
   
    0.466
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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