Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP0337Conserved hypothetical protein. (148 aa)    
Predicted Functional Partners:
hjc
Archaeal Holliday junction resolvase; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family.
  
    0.964
MMP0154
Conserved hypothetical archaeal protein; Belongs to the UPF0288 family.
  
    0.738
MMP0338
Phosphoribosyltransferase related protein; Belongs to the UPF0284 family.
       0.696
MMP0312
Conserved hypothetical archaeal protein.
       0.689
MMP0421
Conserved hypothetical protein.
       0.689
cmd
Carboxymuconolactone decarboxylase:Alkylhydroperoxidase AhpD core domain.
       0.689
MMP0608
2-hydroxyglutaryl-CoA dehydratase (Component A) related protein; Citation: J Mol Biol 2001 Mar 16;307(1):297-308, Appl Microbiol Biotechnol. 2001 Oct;57(3):263-73.
       0.689
atwA
Methyl coenzyme M reductase, component A2; Citation: J. Bact. 1993 175: 3196-3203.
       0.689
MMP0656
Conserved hypothetical protein.
       0.689
MMP1641
Soluble P-type ATPase; Citation: FEBS Lett. 471:99-102(2000).
       0.677
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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