close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0339NUDIX hydrolase; Citation: J. Bio. Chem. (1998) 273: 20924-20928. (171 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase; Citation: R. Cohen Kupiec et. al. FEMS Microbiol Lett. 173, 231-238 (1999).
    
 0.912
rpm
Transcription factor TFIIS:DNA-directed RNA polymerase, M/15 kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
       0.827
rncS
Ribonuclease III family:Double-stranded RNA binding (DsRBD) domain.
  
  
 0.677
MMP0672
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    0.674
MMP0800
Conserved hypothetical Archael protein.
  
    0.616
MMP0338
Phosphoribosyltransferase related protein; Belongs to the UPF0284 family.
  
    0.585
nth1
Endonuclease III homologue; Citation: Nucleic Acids Res. (2001) 29: 604-613.
  
  
 0.582
MMP0547
RecJ related protein; Citation: J. Bact. (2000) 182: 607-612.
  
  
 0.547
nadE
NAD+ synthase related protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.526
pcnA
Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
     
 0.506
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (24%) [HD]