Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
htpXPeptidase family M48; Belongs to the peptidase M48B family. (285 aa)    
Predicted Functional Partners:
ehbQ
Conserved hypothetical protein; Citation: Tersteegen, A. and R. Hedderich. 1999. Eur. J. Biochem. 264:930-43. Curr. Opin. Struct. Biol. 2001; 11:694-700.
  
    0.981
MMP0398
Conserved hypothetical archaeal protein.
  
    0.978
alaS
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.958
mdh
Malate dehydrogenase, MDHII (NADP+-dependent); Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.897
hsp60
Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family.
  
 0.883
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase.
  
  
 0.874
MMP1092
Conserved hypothetical protein.
  
  
 0.872
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.831
MMP1332
NAD binding site:FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.813
MMP1603
Ferredoxin.
       0.804
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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