Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnp3Conserved hypothetical Archael protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (232 aa)    
Predicted Functional Partners:
rnp2
Ribonuclease P-related protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
  
 0.999
rnp4
Conserved hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
  
 0.998
rpl7ae
Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity.
   
 0.996
rnp1
Protein of unknown function UPF0086; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
 
 0.995
MMP1472
Conserved hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
  
   
 0.913
comB
2-phosphosulfolactate phosphatase; Citation: Eur. J. Biochem. 268:5176-5188(2001).
 
    0.862
rps4
SSU ribosomal protein S4P (S9E); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.809
MMP0374
Conserved hypothetical protein.
   
 
  0.802
rpsE
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 0.800
rpsC
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
  0.792
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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