Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rpoE2DNA-directed RNA polymerase subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (58 aa)    
Predicted Functional Partners:
MMP0440
DNA-directed RNA polymerase subunit E'.
  
 
 0.998
rps27ae
SSU ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family.
  
    0.993
MMP0248
DNA-directed RNA polymerase related protein.
   
 
 0.975
spt5
LSU ribosomal protein L24A; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
   
 
 0.973
MMP0442
Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
    0.961
rps24e
SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family.
  
    0.959
rpoH
RNA polymerase H/23 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
   
 
 0.904
rpoB2
DNA-directed RNA polymerase subunit B; Belongs to the RNA polymerase beta chain family.
   
 
 0.877
rpoL
DNA directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
   
 
 0.852
rpoA1
RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.850
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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