STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0470MCM family related protein; Citation: Nucleic Acids Res. 1992; 20: 5571-7. Molec. Microbiol. 1998; 29: 955-961; Belongs to the MCM family. (674 aa)    
Predicted Functional Partners:
MMP0469
Hypothetical protein.
  
    0.986
MMP0472
Probable integrase/recombinase; Citation: J. Mol. Biol. (2003) 330: 15-27, PNAS (2001) 98: 652-657.
  
    0.982
MMP0471
Conserved hypothetical protein.
  
    0.981
dnaB
DNA polymerase family B; Citation: J Bact 176:6402-6403 1994. Genes. Genet. Syst. 1998; 73: 323-336.
  
 0.976
MMP0467
Hypothetical protein.
  
    0.958
MMP0466
Hypothetical.
  
    0.946
MMP0122
Conserved hypothetical protein.
  
 0.938
rpa
Replication protein A; Citation: PNAS (1998) 95: 14634-14639, Annu. Rev. Biochem. (1997) 66: 61-91.
  
 0.938
priS
DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
 
 0.897
rfcA
Replication factor C, small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily.
 
 
 0.893
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.